Category: Science

The Sound Of Settled Science

Gout is often associated with drinking too much or not eating healthily enough, but research suggests genetics play more of a factor in developing the arthritic condition than previously thought.[…]

“Gout is a chronic disease with a genetic basis and is not the fault of the sufferer – the myth that gout is caused by lifestyle or diet needs to be busted,” said epidemiologist Tony Merriman from the University of Otago in New Zealand, when the study was published last year.

47: NIH Under Lockdown

Birthing persons and trans-kids hardest hit.

Confusion and anxiety is rippling through the US health-research community this week following Donald Trump taking office as the 47th US president. His administration has abruptly cancelled research-grant reviews, travel and trainings for scientists inside and outside the National Institutes of Health (NIH), the world’s largest public biomedical funder. Adding to the worry: the Trump team appears to have deleted entire webpages about diversity programmes and diversity-related grants from the agency’s site.

The cancelling of meetings and travel is part of a pause in external communications issued on 21 January by the NIH’s parent organization, the US Department of Health and Human Services (HHS). Researchers who spoke to Nature say that although a short, daylong pause in communications at US agencies has occurred in the past when new administrations have started, to reorient strategy, the reach and length of the Trump team’s — it is set to last until at least 1 February — is unprecedented. Without advisory-committee meetings, the NIH cannot issue research grants, temporarily freezing 80% of the agency’s US$47-billion budget that funds research across the country and beyond.

Related savagery: Questioned by reporters in North Carolinaabout the removal of Anthony Fauci’s security detail – “He made a lot of money. He can pay for his own security.” Will you feel responsible if something happens to him? – “No.”

Mann Down

National Review- Pay Up, Mr. Mann

For more than eight years, the climate scientist Michael Mann harassed National Review through litigation over a blog post — until, eventually, the First Amendment brought an end to his attack. This week, a court in our nation’s capital ordered Mann to pay us $530,820.21 worth of attorney’s fees and costs, and to do so within 30 days. It is time for him to get out his checkbook, and sign on the dotted line.

Trust The “Science”

National Post- Ottawa-funded social justice research isn’t science

The now-widespread practice of requiring researchers to submit statements affirming their commitment to DEI with their applications for jobs and grants incentivizes lying, Prof. Geoff Horsman, a Wilfrid Laurier University biochemist, told the committee in early December. Some grant applications even evaluate socioeconomic and environmental impacts — which is open to the interpretation of those granting the funds.

The Sound Of Settled Science

SciTechDaily;

UCLA chemists have discovered a major flaw in a fundamental rule of organic chemistry that has held for 100 years. They say it’s time to rewrite the textbooks.

Organic molecules, which are primarily made of carbon, have specific shapes and arrangements of atoms. Molecules called olefins contain double bonds, or alkenes, between two carbon atoms. Typically, these atoms and their attached groups lie in the same 3D plane, and deviations from this structure are rare.

The rule being questioned, known as Bredt’s rule, was established in 1924. It asserts that molecules cannot have a double bond at the “bridgehead” position—the junction of a bridged bicyclic molecule—because this position would distort the geometry of the double bond. Bredt’s rule has constrained the design of synthetic molecules by preventing chemists from creating certain structures. Since olefins play a critical role in pharmaceutical research, Bredt’s rule has limited the types of molecules that scientists could envision, potentially holding back innovations in drug discovery.

h/t

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