The Sound Of Settled Science

We are all mutants now…

We are all mutants. The 3bn pieces of DNA that make us who we are were long thought to be constant, chiselled in granite like a classical monument, with only tiny changes made here and there. Scientists used to believe that DNA mutations were largely harmful.
By the late 1990s and early 2000s, as the first sequences of the human genome came rolling in, researchers realised that their view of mutations was completely backwards. Instead of being rarities that almost inevitably harm health, mutations litter the human genome. The average human carries around 400 unique mutations, and most of us are none the worse because of them.
This challenged some basic tenets of genetics, as well as they ways that scientists and physicians interpreted genetic tests.

7 Replies to “The Sound Of Settled Science”

  1. So … does this mean that the GAY-gene is … normal ? The TRANS-gene is … normal ? Perhaps this is nature’s attempt at population control ?

  2. no kenj, it means that evolution is alive and well, it’s scale were understand falls apart.

  3. To be silly I’m thinking the scientists found what they think is a gay or trans gene, so now they have to change tune and say mutations are normal. Haha
    But in all seriousness what is actually happening is that stupid man is thinking it can figure out creation. But man can’t so it just pathetically flops around like a fish out of water instead. Hahaha

  4. This article fails to persuade. Every case cited demonstrated variants of unknown or uncertain significance (VUS) to be harmful even when classified as benign.
    “The average human carries around 400 unique mutations, and most of us are none the worse because of them.”
    The above quote is the author’s interpretation which is totally unsupported.
    Normal ≠ Mutant
    Genetic counseling must be a pretty good racket for elitist progressive know-nothings.
    “A small study in Psycho-Oncology surveyed 24 women with breast or ovarian cancer who had received VUS results for their genetic testing. Many of them had a distorted perception of what those results meant. Although two-thirds correctly remembered three years later that the variants detected by the test were unclassified, 79% interpreted the results as a higher genetic risk for developing cancer. One-third had also made significant medical changes in their lives based only on their test results, which Resta and Caleshu do not recommend.
    And they were correct to do so. This argument is usually used against people who do not have cancers. These people already do. Asking a cancer patient to not associate a demonstrated mutation in a gene specifically known for causing their type of cancer with their cancer is ridiculous. Furthermore, the three year survival rate at a minimum 79% is phenomenal considering ovarian cancer patients were included in the study. Looks like the one-third were right and are alive to talk about it.

  5. could this be the reason that people are getting dumber with each generation? captcha “doctor evolu”

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