The Sound Of Settled Science

During a decade as head of global cancer research at Amgen, C. Glenn Begley identified 53 “landmark” publications — papers in top journals, from reputable labs — for his team to reproduce. Begley sought to double-check the findings before trying to build on them for drug development.
Result: 47 of the 53 could not be replicated.

Well, it’s probably nothing. (h/t Black Mamba)

53 Replies to “The Sound Of Settled Science”

  1. You mean scientific studies don’t have to be reproducible? Well, that’s going to make it a lot easier! Perpetual motion and anti-gravity here we come!

  2. JB1000 “You mean scientific studies don’t have to be reproducible? etc.”
    You mean “Social (cough cough) *sciences* here we come”
    Legions of useless leftard hacktivists depend on their comfortable lairs in whackademia to ply their mind poisoning trade.
    And about as useful as what you described.

  3. Society becomes more and more immoral and dishonest, unwilling to concede
    that the normal failures and mistakes made in life are individual responsibilities.

  4. I am so sick of this goof shit.
    Yes I just compared CAGW activists to prison slang for pedophiles.
    See you in Court, mofos. I Majored in Philosophy.
    With a Minor of KICKING ASS.
    dale wright,doxet and alive.

  5. A rather timely post! I am currently reading Jules J Berman’s “Machiavelli’s Laboratory” …. it talks about the very problem with falsification and fabrication of data, the art of scientific misinterpretation, the art of obtaining grants, gov’t and corporations and evil science. He writes it as a spoof but it ain’t! Available as a free download from: http://www.julesberman.info/integ/machfree.htm.
    Enjoy

  6. [quote]a hypercompetitive academic environment that fosters poor science and even fraud, as too many researchers compete for diminishing funding.[/quote]
    Penn State has a huge problem.. who cares!!

  7. We need more Begleys and we need to celebrate way more than the ‘groundbreakers’ that get so much media attention. There are dozens of things that can go wrong in a biological experiment. This is more damaging to science than all the Jenny McCarthy’s of the world.

  8. Posted by: LAS at April 2, 2012 1:34 AM
    I Googled her, eww she would take one look at my non black frame glasses and consider me not hipster enough to date her.
    Creep.
    dale wright

  9. Especially Hipster d-bags that wear FAKE glasses (non Proscription Lenses are an insult to the eyesight challenged.
    sarc
    Douchbags.
    I might as well be Black.
    Dale Wright.

  10. My pity inducing eyesight, just so you can be “IRONIC”
    Frack You Douchenozzle.
    Dale Wright.

  11. Proscription Lenses
    Those would be the ones that only let you see the things you’re allowed to see?
    Has anyone told Rick Sanctimonious about them?

  12. Proscription Lenses
    Those would be the ones that only let you see the things you’re allowed to see?

    Yes, they’re quite popular with people who don’t want to see anything that conflicts with their preconcieved notions.

  13. What do you expect from welfare students with an Occupier Mindset being churned out of Canadian Puppy Mill Universities with useless degrees which guarantee them a job at minimum wage in a day care. Which the dummies have taken on debt to pay for, because they were told that University would guarantee them the world without having to earn it. Half the Universities in Canada could be shut down and no body would notice. Most of them exist on a scale of Tax Payer Welfare that would make Bombardier Blush. The cost to the Taxpayer is enormous. About $60,000 per student for 4 years of scholarly fantasy. And that does not include the cost of Foreign Students at the Puppy Mills who also get their Free Healthcare etc paid for by Canadian Taxpayers. The Universities are Tax Supported Puppy Mills churning out uneducated Liberal Nitwits who think we owe them a living for their bad choices……

  14. As black comedian Chris Rock said about medical research, ” There’s no money in the cure, it’s the comeback. They ( medical research ) haven’t cured anything since polio.”
    We have yet again another rent seeking bureaucracy. As Nobel economist James M. Buchanan pointed out in his Public Choice writings, the/any bureaucracy is dis-incentivized to solve it’s problem it was supposedly set up for. Problem solved=no more hack jobs/career/pension=off to the dreaded private sector. Bureaucracies have every incentive to grow the problem.
    There is no reform. King is dead, meet the new king. The reform is the new form under the same incentives.
    Reforming is striking at the branches letting the bureaucratic weeds grow up again. The only way to kill, to use round-up on the choking, non productive bureaucracies is tax revolt. Starve the cancer cells of the modern state. It need not be all out, just a tipping point where the state will roll over dead, like a overloaded ferry to no where.
    It’s us, or them.

  15. Wow! Thanks Kate and Black Mamba, I think.
    This is another horrific way in which our universities have become a force for evil.

  16. I think the good sergeant above makes the key point. I think you’ll gain more credibility as a researcher if you just admit you screwed up or can’t produce the result you were testing for, rather than being later found out for a fraud. “Publish or perish” isn’t a bad paradigm (it’s as close to capitalism as you get in academia), but if you want to write fiction, perhaps a career in science isn’t for you.
    …oh, wait. Sorry. I got confused between “credibility” and “funding” again. Never mind.

  17. Paul @ 7:59:
    Sure, one way is to starve our institutions to death. But we also need them, although not, of course, in their present corrupted form. So, do we have to kill them, or can we reform them without first killing them? At the moment, my money’s on the latter.

  18. Now a Sociology professor from a University whose mascot quacks wants to punish you for not believing the AGW fraud.
    I am a skeptic. I look at the money, and I look at character, and I decide how important the issue is, and I decide how much I will take on faith and how much proof I require.
    Here’s a hint, people. If it doesn’t stop you from jetting off to Rio for a conference, it’s not enough for me.

  19. nick @ 9:37: in which by “latter” I should like to be understood to have meant “former”.

  20. I’m surprised this article of common sense appeared in Nature since junk science is their forte. If an article has any kind of global warming angle Nature prints and promotes it.

  21. Weill that just makes it soooo comforting that sooo many sheep think it is ok to let the experts decide how we should live because they are …well experts and have such knowledge, integrity and all that peer review process to make sure it is all kosher…
    Make me want to vomit, because all aspects of society, be it politicians, scientists, teachers, whatever, are riddled with human beings and human beings are….. well frickin human with all the weaknesses, greed and motives that entails.

  22. ancer research is a racket. If money bought cures we would be rid of cancer by now. Fact is the real cancer is greed – greed in the skanks who put on a charity front and line their pockets with the proceeds.
    Beside that we have a government and administrative class who drank the green globalist Koolaid and think there are far too many of us “cancers on the earth” and 9 in 10 have to check out before they see the green utopia. Cancer figures into their plan of population control quite well. Please note that at the turn of the 20th century on 1 in 100 people contracted a form of leathal cancer now it’s one in three – just what is it about cancer they are researching, cures or causes??

  23. Think of the mice, won’t you please think of the mice!? They have cured almost everything in mice, cancers, strokes, MS, Aids, you name it. Mice have been living in the belief that they are immune to today’s scourges and now you say that it’s all fake? Woe is mouse…

  24. The Grey Lady said: “Weill that just makes it soooo comforting that sooo many sheep think it is ok to let the experts decide how we should live…”
    Yep. Even Plato, who proposed the whole thing in the first place, assumed his Philosopher King would actually -know- stuff and not be just another average @sshole with an inflated drive to dominate.
    There are some extremely cool things being done out there these days, but the level of fraud in mainstream science and the attendant literature is simply massive. I’d say appalling, but really nobody has taught scientific ethics as anything other than a way to fabricate an excuse for doing what you want for 30 years at least.
    Like with the mammoths they’re supposedly cloning. I’m going to want to pet one before I get out my wallet, know what I mean?

  25. nick @ 9:37: in which by “latter” I should like to be understood to have meant “former”.
    Posted by: nick at April 2, 2012 10:08 AM
    Edited for a non-Royal personage:
    re: nick @ 9:37: I meant “former” not “latter”.

  26. Still bilking the public after all these years, Cancer is so common it should have been understood and controlled years ago, but we cant have that now can we?

  27. Cancer is so common it should have been understood and controlled years ago, but we cant have that now can we?
    It was understood 4000 years ago.
    Lev_7:23 “Speak unto the sons of Israel, saying, “Ye shall eat no manner of fat, of ox, or of sheep, or of goat.

  28. This is the most telling quote: “I explained that we re-did their experiment 50 times and never got their result. He said they’d done it six times and got this result once, but put it in the paper because it made the best story. It’s very disillusioning.”

  29. What happens in universities is that these research centres become, effectively, fiefdoms supported in large part by external grants.
    In order to keep receiving the grants, the centre must publish – and produce ‘newsworthy’ results. So, the pressure to fudge data, to rush tests, is strong. Furthermore, these centres become focused around one or a few key research directors. These directors select the people who may work in these centres – and these graduate students are also funded by external grants. Therefore, the students must not challenge the work of the director. This entraps the work even more.
    As for solving cancer, I doubt that this will ever happen. It is, after all, not caused directly by an external agent, such as found in malaria, or the plague, or polio etc. It’s a mutation of cells existing within the body and these actions aren’t always so neatly defined, limited, or controllable. We can reduce some causes (pollutants) but I have my doubts whether we will be able to ever, banish it from our world.

  30. Yes fiddle Vegans never get cancer….sheesh.
    Vegetable fat is just as harmful, especially when exposed to high temps. The only oil not harmful is olive oil, cold pressed.

  31. Anyway, you don’t read too well. There is meat as well as fat on cattle, sheep and goats.

  32. so maybe this explains why after 40 years and billions of dollars in research there is no cure for cancer which have killed a number of my immediate family. who never smoked by the way or worked in a coal mine.

  33. It has never been about finding a cure. Always about making money and keeping shareholders happy. The holy grail has always been a few expensive pills a day to maintain the status quo and keep the patient alive. A cure is self defeating for big pharma. Simple logic clearly explained below.
    http://www.youtube.com/watch?v=AazObF_pHSU

  34. About cancer research racket. On the plus side it keeps the kids out of law school, so we have that going for us, which is nice.

  35. If the market was paying for the research the forkupas and frauds would be starving qand in jail…. the problem is public funding handed out by bureaucrats …. knob hughs.

  36. We live in an era . Where Medicine is being taken over by Superstition. Greek Physicians where quite competent for what they knew. By the end of the Empire most where quakes. What makes most people think we won’t end up the same way? Just look at Homeopathy, Mega-vitamins, & other bogus paths to eternal youth. A good diet with exercise will do more for you than all the herbs on the Planet.
    To me this is just another marker of decline. Just like population fall off, & mass migration.
    Politicians making so many silly rules for even nurturer reasons.

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