Curious to know what conditions trip SVEP1 toward making the protein which in turn causes a lot of problems, especially inflammation. (That’s why baby aspirin is so effective. Yeah it thins the blood but more importantly it reduces the inflammation.) Veterinary medicine showed us years ago that you can reverse atherosclerosis in pigs by feeding copious amounts of dietary pectin. (I think they used grapefruit rinds.) Pairing the current article with this: https://www.sciencedirect.com/science/article/abs/pii/S2210523912000621 “The present study demonstrates that LM pectin would be a more efficient anti-inflammatory agent than HM pectin upon oral administration. LM pectin was found to inhibit both local and systemic inflammation, whereas HM pectin was shown to prevent intestinal inflammation.”
So the science here is actually compelling. For a long time it seemed veterinary medicine, followed by integrated (holistic) medicine was way ahead. Now (I think largely because of the internet, and subsequent market factors) the “western” medicine purists have been forced to concede a lot, listen, and begin to capitalize on stuff we knew about for a long time. And, yeah, I never thought cholesterol was a smoking gun.
You know a whole lot more than I do on this subject, and your links are quite technical. Anyway, I am happy, as I love grapefruit and lemons.
Kate and you know how to breed animals with good results. Mating of humans is also important. We do it by self-selection with uncertain results. I would not want that to change.
This science has been unsettled for decades. I have read all of this since 1970.
Genetics is likely the best clue.
My late husband died at age 47, almost 30 years ago. He was diagnosed at age 22 with the potential for heart issues and with hyperlipoprotenemia at about age 27, basically high cholesterol readings. In his 30’s, he quit smoking, lost weight and took up running, but still had high cholesterol readings and then high blood pressure by age 40. He was monitored and treated by experts of the day, but also had a very busy job. As a family, we learned from the get-go to cook by draining fat off everything, eating more chicken than beef, fewer eggs and using oat bran, all “folk remedies” of the day. He was not a perfect adherent to the “then received wisdom”. Anyway, medical knowledge/meds/behavioral changes ALL were a fail, as he died a week after passing a heart stress test.
His dad died at age 49 too. One brother, who also had diabetes and a “band lifestyle”, died at age 37.
Genes matter a LOT, for personality, IQ, abilities and possibly interests, via correlation with the former. If you are clumsy playing ball due to heredity, for example, you will gravitate to stuff that you do well, maybe chess or accounting.
The research on DNA is probably the most interesting scientific development in my lifetime. It continues to provide insights that I learned in my teen and university years just by thinking and listening to parents.
Curious to know what conditions trip SVEP1 toward making the protein which in turn causes a lot of problems, especially inflammation. (That’s why baby aspirin is so effective. Yeah it thins the blood but more importantly it reduces the inflammation.) Veterinary medicine showed us years ago that you can reverse atherosclerosis in pigs by feeding copious amounts of dietary pectin. (I think they used grapefruit rinds.) Pairing the current article with this:
https://www.sciencedirect.com/science/article/abs/pii/S2210523912000621
“The present study demonstrates that LM pectin would be a more efficient anti-inflammatory agent than HM pectin upon oral administration. LM pectin was found to inhibit both local and systemic inflammation, whereas HM pectin was shown to prevent intestinal inflammation.”
So the science here is actually compelling. For a long time it seemed veterinary medicine, followed by integrated (holistic) medicine was way ahead. Now (I think largely because of the internet, and subsequent market factors) the “western” medicine purists have been forced to concede a lot, listen, and begin to capitalize on stuff we knew about for a long time. And, yeah, I never thought cholesterol was a smoking gun.
You know a whole lot more than I do on this subject, and your links are quite technical. Anyway, I am happy, as I love grapefruit and lemons.
Kate and you know how to breed animals with good results. Mating of humans is also important. We do it by self-selection with uncertain results. I would not want that to change.
This science has been unsettled for decades. I have read all of this since 1970.
Genetics is likely the best clue.
My late husband died at age 47, almost 30 years ago. He was diagnosed at age 22 with the potential for heart issues and with hyperlipoprotenemia at about age 27, basically high cholesterol readings. In his 30’s, he quit smoking, lost weight and took up running, but still had high cholesterol readings and then high blood pressure by age 40. He was monitored and treated by experts of the day, but also had a very busy job. As a family, we learned from the get-go to cook by draining fat off everything, eating more chicken than beef, fewer eggs and using oat bran, all “folk remedies” of the day. He was not a perfect adherent to the “then received wisdom”. Anyway, medical knowledge/meds/behavioral changes ALL were a fail, as he died a week after passing a heart stress test.
His dad died at age 49 too. One brother, who also had diabetes and a “band lifestyle”, died at age 37.
Genes matter a LOT, for personality, IQ, abilities and possibly interests, via correlation with the former. If you are clumsy playing ball due to heredity, for example, you will gravitate to stuff that you do well, maybe chess or accounting.
The research on DNA is probably the most interesting scientific development in my lifetime. It continues to provide insights that I learned in my teen and university years just by thinking and listening to parents.