Gilead Sciences shares surged by more than 15% in after-hours trading Thursday after details leaked of a closely watched clinical trial of the company’s antiviral drug Remdesivir, showing what appears to be promising results in treating Covid-19.
The University of Chicago’s phase 3 drug trial found that most of its patients had “rapid recoveries in fever and respiratory symptoms” and were discharged in less than a week, health-care publication STAT News reported.
“The best news is that most of our patients have already been discharged, which is great. We’ve only had two patients perish,” University of Chicago infectious disease specialist Kathleen Mullane said, according to STAT News, which obtained a video of her remarks.
Related: Dow futures rip 800 points
Update: Trump Announces 3-Phase Guidelines for Governors to Reopen States
So now it’ll become the “Wuhoo Flu”, if an effective treatment plan is developed.
News writers will have shift gears from being CCP propaganda spreaders:
“And now from the desk of the Daily Apocalypse…!” the end of the world has been cancelled.
The new and improved “cancel culture”.
Cheers
Hans Rupprecht – Commander in Chief
Army Group “True North”
1st Saint Nicolaas Army
It’s so frustrating to not have a leader in this country. Trump’s plan sounds so sensible it might not get attacked, except by complete idiots like Acosta and the MSNBC cast.
Nope. The WHOLE Media Party in the States will attack attack attack till November 3rd. And our Idiots here in Canada will repeat repeat repeat. Count on it.
See what happens when the grown-ups do medical science properly? You get good things. There are several studies looking at Remdesivir, and let’s hope the published findings match the hype.
The one downer here is that it must be taken intravenously (I think), so treating people at home may be problematic.
Could be worse it could be a horse pill sized suppository 🙂
Doesn’t matter. If people can be treated, that’s all that matters.
So how is this study so different from what Zelenko did?
He administered to 350 ( now up to 1000 I think) and had no deaths.
That’s what he determined as the definition of success. No deaths.
So here we have a small sample that seems to define success as patients got better and only 2 died.
And Gilead ads about 13 billion to its market cap as a result.
I guess a big difference would be no one was going to get rich on the Zelenko protocol
I see the test was done in Chicago.
I wonder how many dems got in on GILD before the market closed.
Dr. Zelenko did not do a study as far as I know. He hasn’t published anything, nor has anyone reviewed his work, so there is no way to independently evaluate his treatment. The institution of medical science is rightly skeptical of fantastic claims. The study process has been established to keep out quacks and charlatans, and it works, if slowly.
Agreed. But media sure got excited about this study which is not much different.
Why?
I believe chloroquine likely also helps, but it’s not an anti-viral. I’m not a medical pro, so just my intuition speaking. But I think that chloroquine offers protection to hemoglobin that helps prevent some of the worst damage of the disease. But it only helps and only in that manner. So I believe it’s not a cure-all, and in particular, the protection it brings is not complete, it just gives your immune system some help. So I think in the end, it will be shown as an aid, but not a full treatment. And since it only provides protection in that one manner, it is hard to judge the effectiveness.
Gilead has been shown to have it’s fingers in clandestine pies under the guidance of 3 letter federal agencies doing research for ethnically targeted biological weapons in eastern Europe. Mainstream media is also under the guidance of aforementioned agencies (see operation mockingbird). I would suggest that is the connection.
We ain’t got no time for … if slowly.
As an example, we spend a couple of years (from analysis to verification) putting a new mode in an airborne radar. Mostly that’s more due to the review cycles than the engineering. In peace time, that is proper.
However, when radar was first developed in WWII, the Allies and Germany raced each other, literally daily, to develop radar detection and defensive techniques. If today’s mission revealed that the Germans had overcome a jamming technique, the engineers had to work overnight to find as good a counter as possible, and put it in the planes, because come hell or high water, they had to fly their missions tomorrow.
That’s the mentality we need to have now against the Wuhanvirus. If the Zelenko protocol does no harm (except for manageable side effects) and may do good, and we ain’t got nuthin’ else, you can be playing with people’s lives by withholding it until the la de da … if slowly … study process (which takes years) is completed.
Besides Dr. Zelenko, many dozens, perhaps hundreds of doctors around the world, have found the Zelenko protocol to be effective. A Democratic politician in, I think, Michigan publicly thanked President Trump for the suggestion as she was given the treatment and made a full recovery.
A doctor should just inform his patient that this is a technique that some had found success with, but is experimental and has not been verified by a study published in a medical journal, and let the patient make his own decision. I bet most would jump at it. I would, and I have a doctorate in STEM, and spent my whole life doing it, and understand what is involved in not just a review cycle for a paper, but product verification for sell off.
So exactly what had been the arguments against the Zelenko protocol?
All the drugs involved had been in use for a long time, with well known side effects.
We have enough data (not just from Dr. Zelenko) to determine the exact effect with a small margin of error.
And the drugs are relatively cheap and available.
As you said, to some perhaps the last point is a negative.
The argument against it is it hasn’t been tested. There are indications, but no proof as yet. For the protocol to be adopted you would have to prove the recovery seen in the treated patients was due to the intervention, and not chance. Given that the vast majority of COVID patients recover without a trip to the ICU, how do we know the result was due to the treatment and not some other factor? What role does luck play? For example, I could treat a university’s track and field team that has been exposed to the virus with my grandmother’s poultice recipe, and they would likely all recover. Does that make my grandmother a miracle worker?
He may be on to something, but more, and more careful, study is needed. People have been banging on about this treatment with much more feeling than the evidence warrants. Reason will get us a treatment, but we may have to be patient.
The safety and off-label use of hydroxychloroquinine has been been explored to the nth degree.
https://doi.org/10.1177%2F0961203396005001131
I am in a related field with a STEM-PhD and well understand off-label.
HCQ and Zelenko protocol and the Raoult protocols show enough evidence to indicate some form of efficacy. If this was not the case, then why did Apotex in Ontario donate millions of doses for drug trial on Ontario physicians and nurses?
Remsdevir and “future vaccines” etc etc are just for a quick buck. There will never really be an effect vaccine anyway.
The Doctors & Nurses are going to determine the best Protocol for their patients….The idea that anything has a rigidly tested advantage is B S for brains. The “It’s not tested” needs to be curb stomped….
The Academic morons need to go sit on the power line with the other Crows, they add nothing to saving lives….
There was no argument against it. All the opposition was based purely on the fact that Donald Trump had recommended it, and ignored all the prim research types who want to do ages long double-blind studies so they could do their fine statistical analyses. He rejected the experts opinion, once again, and instead went with the common sense and humane urge to help sick people despite the experts hurt feelings.
Exactly. And while I hope Gilead’s Remdesivir proves effective for the ChiCom-19 Virus … I find the sudden public (and major institutional investor) enthusiasm for the drug to, essentially, be an anti-Trump expression. See! They’ll say! Trump was peddling snake oil (hydroxychloroquine) but HERE is a REAL Biotech Company … with a REAL drug. Trump’s drug was phony! I just get this creepy feeling that Remdesivir is a politically-correct ChiCom-19 drug.
Sadly, it appears to me that we are doing science and investment on a “social-science” basis … more than a biological-science basis. The FORTUNES flowing into Gilead at the moment appear to be more akin to irrational exuberance… than proven science.
Again. Don’t get me wrong, but I have read that we have successfully created antivirals for only about 25% of all viruses we’ve attempted. It will be nice if this antiviral is in the 25% … but literally, the odds are against it. But … even if it works only sometimes, for some people … it will be a useful therapy. As OB said … more or less … when your cow is in the ditch … any rope will do. And that should include the hydroxychloroquine regimen too … as we already know that it works very, very, well … for many people
“There was no argument against it. ”
The argument against is there’s no solid evidence for it and recent trials are going poorly.
“He rejected the experts opinion”
Like the retard he is. As GG said, leave this up to the people who know what they’re talking about.
So I reckon U.S. Senators will be buying major stock in Gilead Sciences?
Gilead already has former high ranking us officials either on its board or in other less visible places of power.
Here’s the thing. Hydrochloroquinine, plus zinc, also showed promise. At the same time that some doctors saw great results, other doctors did not. But Hydrochloroquinine itself does nothing, it is the zinc that does it, but it needs the HCQ to get into the cells to do it. The action of zinc is to prevent the virus from infecting the cell. That results in the virus not being able to replicate, so less virus, and an uninfected cell. But if the cell is already infected, HCQ plus zinc will do nothing, and if you already have too many infected cells, well, nice knowing you. Thus, some doctors reported great results, because they used HCQ + zinc early, and some reported no results, because, fearing a shortage of HCQ, they only used it on late stage, serious cases, on which it will be ineffective.
Remdesivir appears to be effective on late stage cases, something HCQ is not. The obvious ploy, employ both Remdesivir and HCQ + zinc, the Remdesivir will kill the virus and the HCQ and zinc prevent infection of cells and the virus will have nowhere to go to hide.
A question, will anyone do any actual tests of HCQ, and if they do, will it be reported? And why does the press hate HCQ, even though they are not doctors, will they also hate Remdesivir, because Trump supported it? Will anyone be allowed to test both at once? If it worked even better, would it be praised, or banned and blackballed?
Is the COVID-19 another virus with civil rights, to be protected and nourished?
If you run a poorly designed study, you can make any treatment look bad,
From a Brazilian Study and facts hidden at the bottom of the story. “Beginning March 23, half the participants were given a high dose of 600 milligrams of chloroquine two times a day. Half were given a low dose of 450 milligrams twice a day for the first day and then a single dose each day. The patients also received azithromycin and another antibiotic.”
1200 mg a day. Three times the dose given to a normal Lupus Patient, with no mention of Zinc.
Surprise! Some had heart problems!
https://www.usatoday.com/story/news/2020/04/15/coronavirus-chloroquine-test-halted-drug/2983129001/
Ways to discredit HCG?
Don’t add zinc (many elderly and infirm have low normal zinc levels)
Only give it to very advanced cases (it works best by stopping viral reproduction in early cases.)
HCG is not a silver bullet, but if it helps 20-70% of the patients, it will save hundreds of thousands, and may save civilization.
And here we go. Gilead downplays.
Why did media run with this story that was no different than Zelenkos, which they have gone out of their way to discredit.
Money.
https://www.zerohedge.com/health/gilead-pours-cold-water-report-sent-market-soaring-anecdotal-reports-no-statistical-power
Why are all the Communist States (D) delaying phase 1… Its MONEY… FED Money… When Trump cancels the National Status… They will l be on their own with nobody to steal from.. The usual skin is gone, no stuff falling off trucks….Yes Trump will be responsible for all those who complied with Fed Guidelines and that data proves that the Pandemic (Log) has burnt out… Yes NY & California have deliberately FUBAR’d their dbase by adding random Testing results into the confirmed Case methodology… Should have created a separate dbase because it is a separate issue…We still have stupid PPL who were lucky the first time around and they have a high risk for infection and the virus will get them if we are lucky..
JMHO
Sounds like the same stories I heard about Remdesivir thirty days ago, When they were trying drugs on Chinese patients. It Works! It doesn’t Work. Wait for the studies!
I hope it works. I hope Hydroxy Chloriquine works. I hope we can get a decent vaccine too.
Billions and billions of dollars spent on treatment research and hyper-detailed biological analysis. A century of publically available (or stealable) research in a couple of years.
They are going to take that information and based on this one, work to make the next virus much, much worse. They’ll also learn enough to avoid another accidental release.
Where will it start the next time?
https://www.breitbart.com/national-security/2020/04/16/report-coronavirus-orginated-wuhan-lab/
Yes, but I can guarantee you the United States will build a very robust virus surveillance infrastructure, and forge broad cooperative agreement with morally and technically advanced countries to surveil new threats, and provide a cooperative response. I think that WHO is toast. And the US will go back to cold war levels of strategic stockpiles of drugs and medical equipment. Most of all the naïveté regarding Communist China’s intentions and goodwill towards the world is now a thing of the past.
It certainly should be … the gullible naivety of the West toward the CCP should be OVER. FINISHED. I would LOVE to see a mass American/Canadian consumer boycott of ALL things China. But of course the Bernie Sanders types will always praise the “wonderful” (sic) Commie Chinese.
BTW … I don’t have a real problem with the Three Phases of the Trump reopening of America … it reads as though it came straight from the desk of Dr. Fauci. The only real question is HOW FAST will we roll through these phases? I can only imagine Gavin Newsom isn’t going to be in any hurry to move my State through these phases. Why? “Orange Man bad”
I assume Californians don’t want to be considered Rabid, & shot on sight ,if they didn’t stay Quarantined in California… They would have to follow the Communist States and make a Stand…10 States = 20 Senators…A supper majority against them.. By May 1 they will turn tail & blame Trump… Actually AZ Dr’s have been planning phase 2 since last week….
JMHO