It was my understanding that there would be no gene.
The Nature of Human Nature
A Sam Harris podcast with Robert Plomin about the role that DNA plays in determining who we are.
The Sound Of Settled Science
After cancer-prevention surgeries, women learn BRCA gene test may have been wrong
The Sound Of Settled Science
Three months after his bone marrow transplant, Chris Long of Reno, Nev., learned that the DNA in his blood had changed. It had all been replaced by the DNA of his donor, a German man he had exchanged just a handful of messages with.
He’d been encouraged to test his blood by a colleague at the Sheriff’s Office, where he worked. She had an inkling this might happen. It’s the goal of the procedure, after all: Weak blood is replaced by healthy blood, and with it, the DNA it contains.
But four years after his lifesaving procedure, it was not only Mr. Long’s blood that was affected. Swabs of his lips and cheeks contained his DNA — but also that of his donor. Even more surprising to Mr. Long and other colleagues at the crime lab, all of the DNA in his semen belonged to his donor. “I thought that it was pretty incredible that I can disappear and someone else can appear,” he said.
Mr. Long had become a chimera, the technical term for the rare person with two sets of DNA. The word takes its name from a fire-breathing creature in Greek mythology composed of lion, goat and serpent parts. Doctors and forensic scientists have long known that certain medical procedures turn people into chimeras, but where exactly a donor’s DNA shows up — beyond blood — has rarely been studied with criminal applications in mind.
[…]
If another patient responded similarly to a transplant and that person went on to commit a crime, it could mislead investigators, said Brittney Chilton, a criminalist at the Sheriff’s Office forensic science division.
And it has misled them, Ms. Chilton learned once she began to research chimerism. In 2004, investigators in Alaska uploaded a DNA profile extracted from semen to a criminal DNA database. It matched a potential suspect. But there was a problem: The man had been in prison at the time of the assault. It turned out that he had received a bone marrow transplant. The donor, his brother, was eventually convicted.
Abirami Chidambaram, who presented the Alaska case in 2005, when she worked for the Alaska State Scientific Crime Detection Laboratory in Anchorage, said she had heard about another disconcerting scenario since then. It involved police investigators who were skeptical of a sexual assault victim’s account because she said there had been one attacker, though DNA analysis showed two. Eventually the police determined that the second profile had come from her bone marrow donor.
Similar scenarios could also create confusion around a victim’s identity — and in fact it has, said Yongbin Eom, a visiting research scholar at the University of North Texas Center for Human Identification. In 2008, he was trying to identify the victim of a traffic accident for the National Forensic Service in Seoul, South Korea. Blood showed that the individual was female. But the body appeared to be male, which was confirmed by DNA in a kidney, but not in the spleen or the lung, which contained male and female DNA. Eventually, he figured out that the victim had received a bone marrow transplant from his daughter.
But don’t worry. The same experts who assured this could never happen have also declared that the phenomenon is harmless.
From the comments: Oh great, we’re going to have to learn yet another set of pronouns.
What Could Possibly Go Wrong?
Put your trust in the experts: Instead of wiping them out, genetic engineering may have made [mosquitoes] more ‘robust’
The Sound Of Settled Science
Just when they thought they had it all figured out: Researchers into canine eye disorders discover an “unprecedented mode of inheritance”
The Sound Of Settled Science
Usually, we inherit genes from each of our parent in fairly equal measures. However, there are now approximately 20 reported cases of children inheriting almost all of their genes from a single parent.
I, For One, Welcome Our New Self-Driving Overlords
BREAKING: Prosecutors say they used online genealogical sites to find DNA match for suspected California serial killer.
— The Associated Press (@AP) April 26, 2018
Now we know why Kim Jung Un stepped over the border for a South Korean handshake today.
His side’s winning.
All your DNA are belong to us.
Many of us warned people about this when the fad began. These genealogy database systems are no different than NSA or Facebook databases. There is no privacy aspect. They were predictably going to be harvested by authorities; as they did. https://t.co/eR185TzvjP
— TheLastRefuge (@TheLastRefuge2) April 26, 2018
The Sound Of Settled Science
For many on the academic and journalistic left, genetics are deemed largely irrelevant when it comes to humans. Our large brains and the societies we have constructed with them, many argue, swamp almost all genetic influences.
Humans, in this view, are the only species on Earth largely unaffected by recent (or ancient) evolution, the only species where, for example, the natural division of labor between male and female has no salience at all, the only species, in fact, where natural variations are almost entirely social constructions, subject to reinvention. We are, in this worldview, alone on the planet, born as blank slates, to be written on solely by culture. All differences between men and women are a function of this social effect; as are all differences between the races. If, in the aggregate, any differences in outcome between groups emerge, it is entirely because of oppression, patriarchy, white supremacy, etc. And it is a matter of great urgency that we use whatever power we have to combat these inequalities.
Reich simply points out that this utopian fiction is in danger of collapse because it is not true and because genetic research is increasingly proving it untrue.
Pfft. Even a Neanderthal knows this.
The Sound Of Settled Science
Females’ Eggs May Actively Select Certain Sperm: New evidence challenges the oldest law of genetics.
Sciencing for Napoleon.
We have to stop stigmatizing obese people because it’s not choice, it’s genes.
This is definitely an example of genes over choice /sarc:
Flint points to the fact that the proximity of a fast food restaurant is associated with how much we consume those foods. And not surprisingly, advertising also plays a part.
The story cites this CNN story from March.
And this is the example of genes:
The monogenic obesity syndromes are very rare, Meyre noted, so rare they may collectively represent only 0.5% of the obese population in Canada, while individually some of these syndromes represent one in a million births.
So 33,000 Canadians are genetically obese and 6.6M people in Canada are obese but it’s totally not their fault because genetics.
I guess the real question should be if Global thinks we’re as stunned as their “seasoned fashion and beauty journalist”.
Not Waiting for The Asteroid
Recently terminated Google engineer James Damore chooses Dr. Jordan B Peterson to give his first interview, ahead of any cable news outlet.
On Google’s own YouTube platform no less.
The Sound Of Settled Science
We are all mutants. The 3bn pieces of DNA that make us who we are were long thought to be constant, chiselled in granite like a classical monument, with only tiny changes made here and there. Scientists used to believe that DNA mutations were largely harmful.
By the late 1990s and early 2000s, as the first sequences of the human genome came rolling in, researchers realised that their view of mutations was completely backwards. Instead of being rarities that almost inevitably harm health, mutations litter the human genome. The average human carries around 400 unique mutations, and most of us are none the worse because of them.
This challenged some basic tenets of genetics, as well as they ways that scientists and physicians interpreted genetic tests.
Honey, I Finished The Internet
The making of elite foxes.
Hope For Taz
Facing extinction, the devils have fought back.
The Sound of Settled Science
Stats lesson. Grab a coffee.
How Clones Have Transformed the Game of Polo
The Sound Of Settled Science
Phys Org: UNC School of Medicine researchers discovered a gene called R2d2 – Responder to meiotic drive 2 – that breaks Gregor Mendel’s century-old “law of segregation,” which states that you have an equal probability of inheriting each of two copies of every gene from both parents.
“Organic” Is The Latin Word For “Grown In Pig Shit”
Anti-GMO proponents, today, are the flat-earthers of yesteryear; they worry about falling off the edge.
“Sure you might get a variety of seed that has some beneficial traits, but no one ever took the
time to say, ‘well sure there are some beneficial traits but are they any side effects?’ These
techniques are allowed in organic production.
Or is there more to it? Are they simply enemies of humanity?
The Friends of the Earth and others who oppose such advances want you to die because they believe humans
are a plague on the Earth.
The Sound Of Settled Science
Protein deniers defy consensus;
Open any introductory biology textbook and one of the first things you’ll learn is that our DNA spells out the instructions for making proteins, tiny machines that do much of the work in our body’s cells. Results from a study published on Jan. 2 in Science defy textbook science, showing for the first time that the building blocks of a protein, called amino acids, can be assembled without blueprints — DNA and an intermediate template called messenger RNA (mRNA). A team of researchers has observed a case in which another protein specifies which amino acids are added.
“This surprising discovery reflects how incomplete our understanding of biology is,” says first author Peter Shen, Ph.D., a postdoctoral fellow in biochemistry at the University of Utah. “Nature is capable of more than we realize.”

